Cumulative Small Effect Genetic Markers and the Risk of Colorectal Cancer in Poland, Estonia, Lithuania, and Latvia
The continued identification of new low-penetrance genetic variants for colorectal cancer (CRC) raises the Cleaners question of their potential cumulative effect among compound carriers.We focused on 6 SNPs (rs380284, rs4464148, rs4779584, rs4939827, rs6983267, and rs10795668), already described as risk markers, and tested their possible independen